The purpose of this study were to investigate self-leadership, nursing professionalism, job involvement and turnover intention and to identify factors influencing turnover intention of geriatric nurses working in long term care hospitals. The data of it were collected from the 135 questionnaires of its subjects, the nurses working in long term care hospitals in D province. The collected data were analyzed using descriptive statistics, t-test, ANOVA, Scheffe test, Pearson’s correlation coefficient and stepwise multiple regression analysis with SPSS/WIN 21.0. The results revealed that the nurses working in long-term care hospitals had medium level of turnover intention.. There were significant correlation between self-leadership, nursing professionalism, job involvement and turnover intention. Factors affecting turnover were age, marital status, nursing professionalism. Nursing professionalism was the most influential factor with an explanatory power of 30.6%. Based on the result, to reduce turnover intention of long term care hospital nurses, it is necessary to enhance their nursing professionalism through development of educational program and organizational support, establishment of systematic strategy and creation of suitable environment for enhancement of job involvement, and intervention for the work force management considering the variables related to turnover intention of nurses working in long-term care hospitals are required in order to reduce turnover intention of theses nurses.